Genome-wide association studies for growth traits in broilers

Dachang Dou; Linyong Shen; Jiamei Zhou; Zhiping Cao; Peng Luan; Yumao Li; Fan Xiao; Huaishun Guo; Hui Li; Hui Zhang

doi:10.1186/s12863-021-01017-7

Genome-wide association studies for growth traits in broilers

BMC Genom Data. 2022 Jan 3;23(1):1. doi: 10.1186/s12863-021-01017-7.

Authors

Dachang Dou¹, Linyong Shen¹, Jiamei Zhou¹, Zhiping Cao¹, Peng Luan¹, Yumao Li¹, Fan Xiao², Huaishun Guo², Hui Li¹, Hui Zhang³

Affiliations

¹ Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province; College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, P. R. China.
² Fujian Sunnzer Biotechnology Development Co., Ltd, Nanping, 354100, P. R. China.
³ Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province; College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, P. R. China. huizhang@neau.edu.cn.

Abstract

Background: The identification of markers and genes for growth traits may not only benefit for marker assist selection /genomic selection but also provide important information for understanding the genetic foundation of growth traits in broilers.

Results: In the current study, we estimated the genetic parameters of eight growth traits in broilers and carried out the genome-wide association studies for these growth traits. A total of 113 QTNs discovered by multiple methods together, and some genes, including ACTA1, IGF2BP1, TAPT1, LDB2, PRKCA, TGFBR2, GLI3, SLC16A7, INHBA, BAMBI, APCDD1, GPR39, and GATA4, were identified as important candidate genes for rapid growth in broilers.

Conclusions: The results of this study will provide important information for understanding the genetic foundation of growth traits in broilers.

Keywords: Body weight; Broiler; GWAS; Growth trait; Heritability.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chickens* / genetics
Genome-Wide Association Study*
Genomics
Phenotype
Polymorphism, Single Nucleotide / genetics