Characterization of the novel HLA-DRB1*04:315 allele by next-generation sequencing

HLA. 2022 Jun;99(6):654-655. doi: 10.1111/tan.14534. Epub 2022 Jan 18.

Abstract

HLA-DRB1*04:315 differs from HLA-DRB1*04:07:01:02 by a single nucleotide substitution in codon 147 of exon 3.

Keywords: HLA; bone marrow; next-generation sequencing; novel allele.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Exons / genetics
  • HLA-DRB1 Chains / genetics
  • High-Throughput Nucleotide Sequencing*
  • Humans

Substances

  • HLA-DRB1 Chains
  • HLA-DRB1*04 antigen