Resolution of symptoms after Heller's cardiomyotomy with DOR fundoplication versus endoscopic balloon dilatation in patients with achalasia Cardia at tertiary care hospital

J Pak Med Assoc. 2021 Oct;71(10):2321-2324. doi: 10.47391/JPMA.11-1350.

Abstract

Objective: To compare improvement in symptoms following Heller's myotomy with Dor fundoplication and endoscopic pneumatic dilatation for the treatment of achalasia cardia.

Methods: The prospective comparative study was conducted at the Department of Upper Gastroenterology and Minimally Invasive Surgery, Civil Hospital, Karachi, from February 2016 to January 2019, and comprised patients diagnosed with achalasia cardia on oesophageal manometry. The subjects were randomised into endoscopic pneumatic dilatation group A and laparoscopic Heller's myotomy with Dor fundoplication group B. Eckardt scores were compared between the groups at one-year follow-up. Data was analysed using SPSS 22.

Results: Of the 42 patients, 21(50%) were in each of the two groups. The mean age of patients in group A was 37±12.87 years compared to 34±8.59 years in group B. Treatment success in group A was 11(52%) compared to 21(76%) in group B. Eckardt scores between the groups were significant (p<0.001). Patient satisfaction was significantly more in group B (p<0.05).

Conclusions: The efficacy of Heller's myotomy with Dor fundoplication was found to be greater than endoscopic pneumatic dilatation for improvement in dysphagia and overall patient satisfaction at one-year follow-up.

Keywords: Oesophageal achalasia, Heller’s myotomy, HM, Endoscopic pneumatic dilatation, PD..

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Cardia / surgery
  • Dilatation
  • Esophageal Achalasia* / surgery
  • Fundoplication
  • Humans
  • Laparoscopy*
  • Middle Aged
  • Prospective Studies
  • Tertiary Care Centers
  • Treatment Outcome
  • Young Adult