Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives

Thoraya A Farghaly; Kamal M Dawood

doi:10.2174/1389557522666211229114446

Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives

Mini Rev Med Chem. 2022;22(9):1256-1267. doi: 10.2174/1389557522666211229114446.

Authors

Thoraya A Farghaly^{1

2}, Kamal M Dawood¹

Affiliations

¹ Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt.
² Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukkarramah, Saudi Arabia.

PMID: 34967287
DOI: 10.2174/1389557522666211229114446

Abstract

Despite several reports and reviews addressing the biological significance of pyrazoles and oxazines, no comprehensive work on the pyrazolo oxazine fused ring system has been published so far. We report all biological evaluations on pyrazolo-oxazine derivatives in this mini-review to provide an avenue for medicinal and pharmacological researchers to conduct further in-depth exploration.

Keywords: Pyrazolo-oxazine; analgesic activity; anti-hepatitis (HCV); anticancer; antimicrobial; inhibitory activity.

Publication types

Review

MeSH terms

Oxazines* / pharmacology
Pyrazoles* / pharmacology

Substances

Oxazines
Pyrazoles