Platelet-activating anti-PF4 antibodies mimic VITT antibodies in an unvaccinated patient with monoclonal gammopathy

Affiliations

• ¹ Institut fur Immunologie und Transfusionsmedizin, Abteilung Transfusionsmedizin, Universitatsmedizin Greifswald. andreas.greinacher@med.uni-greifswald.de.
• ² Zentrum fur Onkologie, II. Medizinische Klinik und Poliklinik, Universitatsklinikum Eppendorf, Hamburg.
• ³ Institut fur Immunologie und Transfusionsmedizin, Abteilung Transfusionsmedizin, Universitatsmedizin Greifswald.
• ⁴ Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg.
• ⁵ Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Center for Thrombosis and Hemostasis (CTH), Johannes Gutenberg University Medical Center, Mainz, Germany; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin.
• ⁶ Regional University Hospital Centre Tours, Department of Haemostasis, Tours, France; University of Tours, EA7501 GICC, Tours.
• ⁷ Dept. of Pathology and Molecular Medicine, and Dept. of Medicine, McMaster University, Hamilton, Ontario.