Molecular diagnostics in dermatology: An online survey to study usage, obstacles and requirements in Germany

J Dtsch Dermatol Ges. 2022 Mar;20(3):287-295. doi: 10.1111/ddg.14659. Epub 2021 Dec 28.

Abstract

Background and objectives: Molecular diagnostics (MDx) increasingly gains importance in dermatology and its application is a prerequisite for personalized medicine. The goal of this cross-sectional study was to determine how MDx is implemented in dermatologists' offices in the three fields of oncology, inflammation and infectiology and which hurdles office-based dermatologists face in terms of MDx.

Methods: Physician members of the Association of the German Dermatologists (Berufsverband der Deutschen Dermatologen e. V.; BVDD) were surveyed via an online questionnaire on MDx.

Results: 39.6 % of the 192 participants reported using MDx. Of these, the vast majority used MDx for diagnosing infectious diseases (86.5 % and 44.3 % of users perform MDx for detection of funghi and sexually transmitted diseases, respectively). Only a small minority applied MDx to answer oncological or immunological questions. The major obstacles for non-users as compared to users were difficulties in implementation, lack of expertise as well as time, personnel, and technical availability. Reimbursement was a main issue in both groups.

Conclusions: Despite availability of specific therapies requiring precision medicine, MDx has not yet been broadly implemented in office-based dermatology. To advance MDx, more needs to be done in terms of continuous education, availability of reliable and valid tests, and reimbursability.

MeSH terms

  • Cross-Sectional Studies
  • Dermatology*
  • Germany
  • Humans
  • Pathology, Molecular
  • Surveys and Questionnaires