Xen45 gel stent ab interno trimming for ostium occlusion: case report

BMC Ophthalmol. 2021 Dec 27;21(1):446. doi: 10.1186/s12886-021-02207-8.

Abstract

Background: Despite the XEN gel stent low-risk profile, various complications following the implant have been described, including internal and external occlusion, with a consequent postoperative rise in intraocular pressure (IOP). In this case report we aimed to present a XEN45 stent internal occlusion successfully treated by trimming in situ its proximal end with a 25 G vitreous scissors using a bimanual technique.

Case presentation: A 63-year-old male patient affected by primary open angle glaucoma (IOP = 25 mmHg) and a full thickness macular hole in his right eye, underwent ab-interno Xen gel stent implantation and, 1 month later, a 25 G vitrectomy surgery. Despite a significant IOP reduction after stent implant, 6 days after vitrectomy, IOP increased (25 mmHg) and the conjunctival bleb flattened following occlusion of stent internal ostium by a clot of presumed fibrinous material. The Nd:YAG laser failed to remove the clot, so that we decided to snip a small bit of the proximal end of the Xen tube (about 0,5 mm length) with a 25 G vitreous scissors, using a bimanual technique. In the postoperative day 1 and month 1, the IOP was 8 mmHg and 12 mmHg, respectively. The Anterior Segment OCT confirmed a functional, layered, filtering bleb, and the normal appearance and patency of the XEN proximal segment. No side effects from the intervention were observed.

Conclusions: Ab interno trimming with vitreous scissors of the occluded proximal end of the XEN stent may represent a safe, rapid and efficient method to restore aqueous humor subconjunctival drainage.

Keywords: Case report; Complications; Glaucoma; MIGS; XEN.

Publication types

  • Case Reports

MeSH terms

  • Glaucoma Drainage Implants*
  • Glaucoma, Open-Angle* / surgery
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Stents
  • Tonometry, Ocular
  • Treatment Outcome