Translation of Plant RNA Viruses

Viruses. 2021 Dec 13;13(12):2499. doi: 10.3390/v13122499.

Abstract

Plant RNA viruses encode essential viral proteins that depend on the host translation machinery for their expression. However, genomic RNAs of most plant RNA viruses lack the classical characteristics of eukaryotic cellular mRNAs, such as mono-cistron, 5' cap structure, and 3' polyadenylation. To adapt and utilize the eukaryotic translation machinery, plant RNA viruses have evolved a variety of translation strategies such as cap-independent translation, translation recoding on initiation and termination sites, and post-translation processes. This review focuses on advances in cap-independent translation and translation recoding in plant viruses.

Keywords: cap-independent translation; plant RNA viruses; translation recoding.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Enhancer Elements, Genetic
  • Frameshifting, Ribosomal
  • Plant Viruses / genetics*
  • Plant Viruses / metabolism
  • Protein Biosynthesis*
  • RNA Caps / physiology
  • RNA Viruses / genetics*
  • RNA Viruses / metabolism
  • Viral Proteins / biosynthesis*

Substances

  • RNA Caps
  • Viral Proteins