The Application of Wearable Glucose Sensors in Point-of-Care Testing

Sheng Zhang; Junyan Zeng; Chunge Wang; Luying Feng; Zening Song; Wenjie Zhao; Qianqian Wang; Chen Liu

doi:10.3389/fbioe.2021.774210

The Application of Wearable Glucose Sensors in Point-of-Care Testing

Front Bioeng Biotechnol. 2021 Dec 8:9:774210. doi: 10.3389/fbioe.2021.774210. eCollection 2021.

Authors

Sheng Zhang¹, Junyan Zeng¹, Chunge Wang², Luying Feng¹, Zening Song¹, Wenjie Zhao¹, Qianqian Wang^{1

3}, Chen Liu¹

Affiliations

¹ State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Ningbo Research Institute, Zhejiang University, Hangzhou, China.
² School of Mechanical and Energy Engineering, Ningbo Tech University, Ningbo, China.
³ College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.

Abstract

Diabetes and its complications have become a worldwide concern that influences human health negatively and even leads to death. The real-time and convenient glucose detection in biofluids is urgently needed. Traditional glucose testing is detecting glucose in blood and is invasive, which cannot be continuous and results in discomfort for the users. Consequently, wearable glucose sensors toward continuous point-of-care glucose testing in biofluids have attracted great attention, and the trend of glucose testing is from invasive to non-invasive. In this review, the wearable point-of-care glucose sensors for the detection of different biofluids including blood, sweat, saliva, tears, and interstitial fluid are discussed, and the future trend of development is prospected.

Keywords: biofluids; glucose sensor; non-invasive; point-of-care testing; wearable.

Publication types

Review