Biosensing strategies for diagnosis of prostate specific antigen

Canan Özyurt; İnci Uludağ; Bahar İnce; Mustafa Kemal Sezgintürk

doi:10.1016/j.jpba.2021.114535

Biosensing strategies for diagnosis of prostate specific antigen

J Pharm Biomed Anal. 2022 Feb 5:209:114535. doi: 10.1016/j.jpba.2021.114535. Epub 2021 Dec 11.

Authors

Canan Özyurt¹, İnci Uludağ², Bahar İnce², Mustafa Kemal Sezgintürk³

Affiliations

¹ Department of Chemistry and Chemical Processing Technologies, Lapseki Vocational School, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
² Bioengineering Department, Engineering Faculty, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
³ Bioengineering Department, Engineering Faculty, Çanakkale Onsekiz Mart University, Çanakkale, Turkey. Electronic address: msezginturk@hotmail.com.

PMID: 34954466
DOI: 10.1016/j.jpba.2021.114535

Abstract

Almost from the time of its discovery, the prostate specific antigen (PSA) has been one of the most accurate and most extensively studied indicators of prostate cancer (PC). Because of advancements in biosensing systems and technology, PSA analysis methods have been substantially updated and enhanced as compared to their first instances. With the development of techniques in biosensor technology, the number of PSA biosensors that can be used in the biomedical sector is increasing year by year. Many different recognition elements and transducers have been used in the development of biosensor systems that exhibit high sensitivity, selectivity, and specificity. Here in this review, we provide a current overview of the different approaches to PSA detection.

Keywords: Biosensors; Cancer marker detection; PSA; Prostate specific antigen.

Publication types

Review

MeSH terms

Biosensing Techniques*
Humans
Male
Prostate-Specific Antigen
Prostatic Neoplasms* / diagnosis

Substances

Prostate-Specific Antigen