Synthesis, Reactivity and Antimicrobial Activity of a Series of 2-Arylamino-1,3-selenazoles

Molecules. 2021 Dec 20;26(24):7695. doi: 10.3390/molecules26247695.

Abstract

A series of 2-arylamino-1,3-selenazoles was synthesized and their reactivity was studied. The 2-arylamino-1,3-selenazoles and their reaction products were characterized by various spectroscopic methods and X-ray diffraction. In addition, the antimicrobial activity of the 2-arylamino-1,3-selenazoles in a panel of seven bacteria and fungi was examined.

Keywords: 1,3-selenazole; X-ray structures; antimicrobial activity; metallation reactions.

MeSH terms

  • Anti-Infective Agents* / chemical synthesis
  • Anti-Infective Agents* / chemistry
  • Anti-Infective Agents* / pharmacology
  • Bacteria / growth & development*
  • Fungi / growth & development*
  • Organoselenium Compounds* / chemical synthesis
  • Organoselenium Compounds* / chemistry
  • Organoselenium Compounds* / pharmacology
  • Structure-Activity Relationship

Substances

  • Anti-Infective Agents
  • Organoselenium Compounds