The Analgesic Properties of Corydalis yanhusuo

Molecules. 2021 Dec 10;26(24):7498. doi: 10.3390/molecules26247498.

Abstract

Corydalis yanhusuo extract (YHS) has been used for centuries across Asia for pain relief. The extract is made up of more than 160 compounds and has been identified as alkaloids, organic acids, volatile oils, amino acids, alcohols, and sugars. However, the most crucial biological active constituents of YHS are alkaloids; more than 80 have been isolated and identified. This review paper aims to provide a comprehensive review of the phytochemical and pharmacological effects of these alkaloids that have significant ties to analgesia.

Keywords: Corydalis yanhusuo; alkaloids; analgesia; inflammation; pain.

Publication types

  • Review

MeSH terms

  • Alkaloids / chemistry
  • Alkaloids / isolation & purification
  • Alkaloids / therapeutic use*
  • Analgesics / chemistry
  • Analgesics / isolation & purification
  • Analgesics / therapeutic use*
  • Corydalis / chemistry*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / therapeutic use*
  • Humans
  • Molecular Structure
  • Pain / drug therapy*
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Extracts / therapeutic use*

Substances

  • Alkaloids
  • Analgesics
  • Drugs, Chinese Herbal
  • Plant Extracts