Role of Optical Coherence Tomography Imaging in Predicting Progression of Age-Related Macular Disease: A Survey

Diagnostics (Basel). 2021 Dec 9;11(12):2313. doi: 10.3390/diagnostics11122313.

Abstract

In developed countries, age-related macular degeneration (AMD), a retinal disease, is the main cause of vision loss in the elderly. Optical Coherence Tomography (OCT) is currently the gold standard for assessing individuals for initial AMD diagnosis. In this paper, we look at how OCT imaging can be used to diagnose AMD. Our main aim is to examine and compare automated computer-aided diagnostic (CAD) systems for diagnosing and grading of AMD. We provide a brief summary, outlining the main aspects of performance assessment and providing a basis for current research in AMD diagnosis. As a result, the only viable alternative is to prevent AMD and stop both this devastating eye condition and unwanted visual impairment. On the other hand, the grading of AMD is very important in order to detect early AMD and prevent patients from reaching advanced AMD disease. In light of this, we explore the remaining issues with automated systems for AMD detection based on OCT imaging, as well as potential directions for diagnosis and monitoring systems based on OCT imaging and telemedicine applications.

Keywords: age-related macular degeneration (AMD); computer-aided diagnostic (CAD); dry AMD; optical coherence tomography (OCT); wet AMD.