Diagnosis of Multidrug-Resistant Pathogens of Pneumonia

Diagnostics (Basel). 2021 Dec 7;11(12):2287. doi: 10.3390/diagnostics11122287.

Abstract

Hospital-acquired pneumonia and ventilator-associated pneumonia that are caused by multidrug resistant (MDR) pathogens represent a common and severe problem with increased mortality. Accurate diagnosis is essential to initiate appropriate antimicrobial therapy promptly while simultaneously avoiding antibiotic overuse and subsequent antibiotic resistance. Here, we discuss the main conventional phenotypic diagnostic tests and the advanced molecular tests that are currently available to diagnose the primary MDR pathogens and the resistance genes causing pneumonia.

Keywords: antimicrobial resistance; molecular assays; multidrug resistant bacteria; phenotypic tests; pneumonia.

Publication types

  • Review