Radiofrequency ablation for liver: Comparison between expert eye and hyperspectral imaging assessment

Photodiagnosis Photodyn Ther. 2022 Mar:37:102699. doi: 10.1016/j.pdpdt.2021.102699. Epub 2021 Dec 20.

Abstract

Liver/hepatic cancer (HC) is a disease that roughly afflicts 10% of cancer patients worldwide. HC is in charge of the death of 0.8 million patients on the earth. Multiple approaches, including thermal ablation, target the treatment of HC. In this study, we investigated radiofrequency (RF) ablation. Expert clinicians' visual assessment (VA) dominantly evaluated the outcome of ablation. Inattentively, the disfavors of VA are being subjective and eye-acuity dependent. In support, we propose hyperspectral imaging (HSI) for objective assessment of liver ablation. To verify our proposal, we computed the ablated liver area using VA and HSI. Unfortunately, HSI is a time-intensive technique. To make it less intensive, we present a way of reducing data analysis time. Saving time permits medical decisions, likewise continue or stop RF ablation, to be taken safer and faster. The way to reduce the time for HSI data analysis depends on narrowing the spectral bands of interest to only the most relevant ones to liver chromophores. Liver chromophores change in concentration because of thermal ablation. VA hardly senses these changes, however, HSI does it. Ultimately, the spectral band centered at 630 nm is optimal for objectively support RF ablation decision-makers.

Keywords: Hyperspectral imaging; Liver cancer; Medical imaging; RF ablation; Thermal ablation treatment.

MeSH terms

  • Catheter Ablation* / methods
  • Humans
  • Hyperspectral Imaging
  • Liver / diagnostic imaging
  • Liver / surgery
  • Liver Neoplasms* / diagnostic imaging
  • Liver Neoplasms* / surgery
  • Photochemotherapy* / methods
  • Radiofrequency Ablation*