Parainfluenza viruses: A trigger for type 1 diabetes new onset?

New Microbiol. 2021 Oct;44(4):241-244. Epub 2021 Dec 19.

Abstract

Type 1 diabetes (T1DM) ethiopathogenesis is still being studied, since the role of environmental factors , especially viruses, is not yet clear. This study was conducted on 31 paediatric patients with T1DM at onset. We analysed: Coxsackieviruses A (CoxA), Coxsackieviruses B (CoxB), Echoviruses (Echo); Influenzavirus A and B (IV-A and IV-B); Adenovirus (AdV); Parainfluenza viruses 1-2 and 3 (PiV 1-2-3); Cytomegalovirus (CMV) and Respiratory Syncytial Virus (RSV). Enteroviruses, especially CoxB and Echo, are most represented. Unexpectedly, Parainfluenza viruses were detected in seasonal subgroups, with peaks in autumn and spring, and spread homogeneously in different age groups.

Keywords: Enteroviruses; Parainfluenza viruses; Type 1 diabetes; diabetes ketoacidosis.

MeSH terms

  • Child
  • Diabetes Mellitus, Type 1*
  • Enterovirus Infections*
  • Humans
  • Infant
  • Paramyxoviridae Infections*
  • Respiratory Tract Infections*
  • Seasons
  • Viruses*