Integrated multi-omics data reveals the molecular subtypes and guides the androgen receptor signalling inhibitor treatment of prostate cancer

Jialin Meng; Xiaofan Lu; Chen Jin; Yujie Zhou; Qintao Ge; Jun Zhou; Zongyao Hao; Fangrong Yan; Meng Zhang; Chaozhao Liang

doi:10.1002/ctm2.655

Integrated multi-omics data reveals the molecular subtypes and guides the androgen receptor signalling inhibitor treatment of prostate cancer

Clin Transl Med. 2021 Dec;11(12):e655. doi: 10.1002/ctm2.655.

Authors

Jialin Meng^{1

2

3}, Xiaofan Lu⁴, Chen Jin^{1

2

3}, Yujie Zhou⁵, Qintao Ge^{1

2

3}, Jun Zhou^{1

2

3}, Zongyao Hao^{1

2

3}, Fangrong Yan⁴, Meng Zhang^{1

2

3

6}, Chaozhao Liang^{1

2

3}

Affiliations

¹ Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, P. R. China.
² Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, Hefei, P. R. China.
³ Institute of Urology, Anhui Medical University, Hefei, P. R. China.
⁴ State Key Laboratory of Natural Medicines, Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P. R. China.
⁵ Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P. R. China.
⁶ Urology Institute of Shenzhen University, the Third Affiliated Hospital of Shenzhen University, Shenzhen University, Shenzhen, P. R. China.

No abstract available

Keywords: androgen receptor signalling inhibitor; molecular subtype; prostate cancer; recurrence-free survival.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Androgen Receptor Antagonists / administration & dosage
Androgen Receptor Antagonists / metabolism
Androgen Receptor Antagonists / pharmacology*
Humans
Male
Molecular Typing / methods
Molecular Typing / statistics & numerical data
Prostatic Neoplasms / drug therapy*
Prostatic Neoplasms / genetics
Signal Transduction / drug effects

Substances

Androgen Receptor Antagonists

Publication types

MeSH terms

Substances

Grants and funding