•Ovarian cancer is the most lethal among gynecological cancers.•Carboplatin-based chemotherapy identifies as the main systemic treatment for ovarian cancer patients.•Almost one every three patients treated with carboplatin experiences hypersensitivity reactions.•Patients may experience breakthrough reactions during drug desensitization.•Omalizumab represents a promising new treatment to overcome carboplatin hypersensitivity.
Keywords: Drug desensitization; Hypersensitivity reactions; IgE antibiodies; Omalizumab; Ovarian cancer; Platinum salts.
© 2021 The Authors.