The Determination of Efficacy of CircuCare on Blood Circulation and Metabolism: An Animal Model Study

Comput Math Methods Med. 2021 Dec 2:2021:9934107. doi: 10.1155/2021/9934107. eCollection 2021.

Abstract

Objectives: To determine whether feeding CircuCare to rats improves blood circulation, metabolism, immune regulation, endocrine activity, and oxidative stress.

Methods: 28 eight-week-old male Sprague-Dawley rats were evenly randomized into control and experimental groups. The control group was fed with ordinary drinking water, while the experimental group was fed with CircuCare at a daily dose of 93.75 mg per 300 g of body weight over eight weeks. Both groups were subjected to a swimming test, and blood samples were taken to observe any variations in various biochemical parameters before and after the test. Key Findings. The experimental group's mean swimming exhaustion duration was 53.2% longer and had a significantly higher lactic acid removal ratio. Their mean prostaglandin E2 level and mean glucose, cortisol, and glutathione level (30 minutes after swimming test) were also significantly higher. No undesirable impacts from CircuCare relating to general blood biochemistry values and bone mineral density were reported.

Conclusions: The present results show that CircuCare can be safely used to increase stamina and exercise capability, expedite the metabolism of lactic acid, accelerate muscle repair, and promote the antioxidant activity of cells in rats.

Publication types

  • Retracted Publication

MeSH terms

  • Animals
  • Blood Circulation / drug effects*
  • Blood Glucose / drug effects
  • Blood Glucose / metabolism
  • Bone Density / drug effects
  • Carica / chemistry
  • Computational Biology
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / pharmacology*
  • Endocrine Glands / drug effects
  • Endocrine Glands / physiology
  • Immunity / drug effects
  • Lactic Acid / blood
  • Male
  • Metabolism / drug effects*
  • Models, Animal
  • Oxidative Stress / drug effects
  • Panax / chemistry
  • Physical Exertion / drug effects
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Blood Glucose
  • Drugs, Chinese Herbal
  • Lactic Acid