Pre-meal high-performance inulin supplementation reduce post-prandial glycaemic response in healthy subjects: A repeated single-arm clinical trial

Diabetes Metab Syndr. 2022 Jan;16(1):102354. doi: 10.1016/j.dsx.2021.102354. Epub 2021 Dec 1.

Abstract

Background and aims: High-performance (HP) inulin, a dietary fiber consists of more than 10 fructose polymers, have been shown to reduce post-prandial glycaemic response (PPGR) and could prevent the occurrence of Type-2 diabetes mellitus (T2DM). Currently, there are no data on whether pre-meal HP inulin supplementation could decrease PPGR.

Methods: 8 healthy adults consumed 20 g of formula that contain 60.2% inulin (w/w) dissolved in water. Blood glucose was measured in fasted participants and at 30-120 min after starting to eat a prepared meal. This test was repeated every week with different supplement formulas.

Conclusion: pre-meal HP Inulin formula supplementation could suppress the post-prandial glycaemic response.

Keywords: Blood glucose; Dietary fibre; Glycaemic response; High-performance inulin; Post-prandial.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Blood Glucose
  • Dietary Supplements
  • Healthy Volunteers
  • Humans
  • Insulin
  • Inulin* / therapeutic use
  • Postprandial Period* / physiology

Substances

  • Blood Glucose
  • Insulin
  • Inulin