Comparison of Covid-19 antibody status after vaccination between residents in long-term geriatric care and residents assisted-living facilities

Infect Dis (Lond). 2022 Apr;54(4):292-296. doi: 10.1080/23744235.2021.2014559. Epub 2021 Dec 17.

Abstract

Objective: To compare 2 CoV-SARS-2 ('anti-s') antibody levels after vaccination between residents in long-term geriatric care (LTGC) and residents in assisted-living facilities who had received two doses of the BNT162b2 vaccine. SARS-CoV-2 serology was tested with Quant II IgG CoV-SARS-2. Blood samples were collected 3-4 months after administration of the second vaccine dose.

Results: Anti-s ≥ 50 AU/ml was found in 85.4% of 90 residents in LTGC (median 498 AU/ml) and 94.9% of 214 residents in assisted living (median 728 AU/ml). p = .006. Factors associated with anti-s < 300 AU/ml were multi-morbidity, diabetes mellitus and cancer.

Keywords: BNT162b2 vaccine; Covid-19; elderly; geriatric care; serology.

MeSH terms

  • Aged
  • Antibodies, Viral
  • BNT162 Vaccine*
  • COVID-19 Vaccines
  • COVID-19*
  • Humans
  • SARS-CoV-2
  • Vaccination

Substances

  • Antibodies, Viral
  • COVID-19 Vaccines
  • BNT162 Vaccine