Emulsion Adjuvants for Use in Veterinary Vaccines

Rachel Madera; Yulia Burakova; Jishu Shi

doi:10.1007/978-1-0716-1892-9_11

Emulsion Adjuvants for Use in Veterinary Vaccines

Methods Mol Biol. 2022:2412:247-253. doi: 10.1007/978-1-0716-1892-9_11.

Authors

Rachel Madera¹, Yulia Burakova¹, Jishu Shi²

Affiliations

¹ Department of Anatomy and Physiology, Kansas State University, College of Veterinary Medicine, Manhattan, KS, USA.
² Department of Anatomy and Physiology, Kansas State University, College of Veterinary Medicine, Manhattan, KS, USA. jshi@vet.k-state.edu.

PMID: 34918248
DOI: 10.1007/978-1-0716-1892-9_11

Abstract

The use of emulsion as adjuvants is widely used in veterinary vaccines. Emulsion adjuvants are inexpensive, stable, and relatively easy to prepare into vaccine formulations. Here we describe the preparation of oil-in-water emulsion adjuvant that has been shown to enhance immune responses and protect against diseases in pigs. This emulsion adjuvant and its variations could potentially be used alone or in combination with other adjuvants in veterinary vaccine formulations.

Keywords: Adjuvants; Antigen; Emulsion adjuvants; Oil-in-water emulsion; Saponins; Surfactant; Trichosanthin.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Adjuvants, Immunologic
Adjuvants, Pharmaceutic
Animals
Emulsions
Swine
Vaccines*

Substances

Adjuvants, Immunologic
Adjuvants, Pharmaceutic
Emulsions
Vaccines