The role of mass spectrometry in antibiotic stewardship

Johannes Zander; Michael Paal; Michael Vogeser

doi:10.1016/j.clinms.2018.11.001

The role of mass spectrometry in antibiotic stewardship

Clin Mass Spectrom. 2018 Nov 16:14 Pt A:31-33. doi: 10.1016/j.clinms.2018.11.001. eCollection 2019 Sep.

Authors

Johannes Zander^{1

2}, Michael Paal¹, Michael Vogeser¹

Affiliations

¹ Institute of Laboratory Medicine, University Hospital, LMU Munich, Marchioninistr. 15, 81377 Munich, Germany.
² Laboratory Dr. Brunner, Luisenstr. 7e, 78464 Konstanz, Germany.

Abstract

•EU guidelines claim the need for widespread availability of TDM.•TDM of antibiotics is recognized as an important element of antibiotic stewardship.•However, availability of analytical services for antibiotic TDM is limited.•ID-LC-MS/MS instruments are still mainly restricted to centralized facilities.•Hospital laboratories should implement ID-LC-MS/MS for TDM of antibiotics.

Publication types

Review