FDG avid pulmonary amyloid nodule in a patient with metastatic renal cell cancer on 18F-FDG PET/CT

Marco Enoch Lee; Veronica Chi Ken Wong; Chuong Bui; Robert Mansberg

doi:10.1016/j.radcr.2021.11.029

FDG avid pulmonary amyloid nodule in a patient with metastatic renal cell cancer on 18F-FDG PET/CT

Radiol Case Rep. 2021 Dec 9;17(3):439-441. doi: 10.1016/j.radcr.2021.11.029. eCollection 2022 Mar.

Authors

Marco Enoch Lee^{1

2}, Veronica Chi Ken Wong^{1

3}, Chuong Bui^{1

3}, Robert Mansberg^{1

3}

Affiliations

¹ Department of Nuclear Medicine and PET, Nepean Hospital, Derby St, Kingswood, NSW, 2747.
² Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia, 2052.
³ Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia, 2006.

Abstract

A 60-year-old man with a background of resected clear cell renal cancer and resected colorectal adenocarcinoma presented with a pulmonary mass lesion in the left upper lobe which was avid on 18-F FDG PET/CT. Needle biopsy confirmed metastatic renal cell cancer, which was surgically excised with wedge resection. Follow-up imaging 6 months later demonstrated a second slowly enlarging subcentimeter nodule in the contralateral lung with increasing FDG avidity, suspicious of further small volume oligometastatic disease. Following surgical resection of the second pulmonary lesion, histopathological examination demonstrated nodular pulmonary amyloidosis and no evidence of malignancy.

Keywords: 18F-FDG PET/CT; Bowel cancer; Multiple primary neoplasms; Pulmonary amyloidosis; Renal cell cancer.

Publication types

Case Reports