Despite several reports of the neuropsychiatric effects of coronavirus disease 2019 (COVID-19) in older adults, only a few cases of COVID-related psychosis have been reported in young patients. This case-based review compares the clinical presentations of 2 previously published cases of adolescent patients who developed psychosis in the context of COVID-related complications with a new case of a male adolescent who developed post-COVID psychosis. A discussion to raise clinicians' awareness of COVID-related psychosis in young patients as well as the need for cautious use of antipsychotic medications in this highly vulnerable age group is also provided.
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