Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation

Erika Erickson; Thomas J Shakespeare; Felicia Bratti; Bonnie L Buss; Rosie Graham; McKenzie A Hawkins; Gerhard König; William E Michener; Joel Miscall; Kelsey J Ramirez; Nicholas A Rorrer; Michael Zahn; Andrew R Pickford; John E McGeehan; Gregg T Beckham

doi:10.1002/cssc.202102517

Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation

ChemSusChem. 2022 Jan 10;15(1):e202102517. doi: 10.1002/cssc.202102517. Epub 2021 Dec 16.

Authors

Erika Erickson^{1

2}, Thomas J Shakespeare^{2

3}, Felicia Bratti^{1

2}, Bonnie L Buss^{1

2}, Rosie Graham^{2

3}, McKenzie A Hawkins^{1

2}, Gerhard König³, William E Michener^{1

2}, Joel Miscall^{1

2}, Kelsey J Ramirez^{1

2}, Nicholas A Rorrer^{1

2}, Michael Zahn³, Andrew R Pickford^{2

3}, John E McGeehan^{2

3}, Gregg T Beckham^{1

2}

Affiliations

¹ Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, United States.
² BOTTLE Consortium, Golden, CO 80401, United States.
³ Centre for Enzyme Innovation, School of Biological Sciences, Institute of Biological and Biomedical Sciences, University of Portsmouth, Portsmouth, PO1 2DY, United Kingdom.

PMID: 34914860
DOI: 10.1002/cssc.202102517

Abstract

Invited for this month's cover is the BOTTLE Consortium, featuring Gregg Beckham's laboratory from NREL and John McGeehan's laboratory from the University of Portsmouth. The cover image shows the application of poly(ethylene terephthalate) (PET) hydrolase enzymes on post-consumer waste plastic, towards the development of an enzymatic PET recycling strategy. The Full Paper itself is available at 10.1002/cssc.202101932.

MeSH terms

Burkholderiales*
Hydrolases
Plastics
Polyethylene Terephthalates
Recycling

Substances

Plastics
Polyethylene Terephthalates
Hydrolases