Standard Membrane Feeding Assay for Malaria Transmission Studies

Methods Mol Biol. 2022:2410:597-606. doi: 10.1007/978-1-0716-1884-4_32.

Abstract

Traditional and modern approaches have been applied to combat the malaria disease. Malaria eradication is a priority in several developing countries. Transmission-blocking vaccines are one of the suggested solutions for malaria eradication. Therefore, there is a demand for introducing the new targets and evaluation methods. Standard membrane feeding assay is the base of the evaluation process of transmission-blocking candidate molecules. Hence, this process is explained in this chapter in detail.

Keywords: Blocking activity analysis; Standard artificial membrane feeding assay; Transmission-blocking intervention.

MeSH terms

  • Biological Assay
  • Humans
  • Malaria Vaccines*
  • Malaria* / prevention & control
  • Malaria, Falciparum
  • Membranes
  • Plasmodium falciparum / immunology

Substances

  • Malaria Vaccines