Fatballs foster fabulous follicles

Joanna L Turley; Ed C Lavelle

doi:10.1016/j.immuni.2021.11.009

Fatballs foster fabulous follicles

Immunity. 2021 Dec 14;54(12):2695-2697. doi: 10.1016/j.immuni.2021.11.009.

Authors

Joanna L Turley¹, Ed C Lavelle²

Affiliations

¹ Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2 D02R590, Ireland.
² Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2 D02R590, Ireland. Electronic address: lavellee@tcd.ie.

Abstract

Adjuvants can be incorporated into vaccines to enhance the magnitude and functionality of adaptive immune responses. In this issue of Immunity, Alameh et al. (2021) reveal that lipid nanoparticles, which are key components of effective SARS-CoV-2 mRNA vaccines, have broad adjuvant function, enhancing B cell responses and protective efficacy of protein-based subunit in addition to mRNA antigens.

Publication types

Comment

MeSH terms

Adjuvants, Immunologic
COVID-19*
Humans
Liposomes
Nanoparticles
SARS-CoV-2
mRNA Vaccines

Substances

Adjuvants, Immunologic
Lipid Nanoparticles
Liposomes
mRNA Vaccines