Anthropometric clinical indicators of visceral adiposity as predictors of nonalcoholic fatty liver disease

Rev Assoc Med Bras (1992). 2021 Nov;67(11):1544-1549. doi: 10.1590/1806-9282.20210316.

Abstract

Objective: This study aims to evaluate the role of anthropometric clinical indicators of visceral adiposity as predictors of NAFLD, identifying the cutoff points based on gender.

Methods: This was a cross-sectional study conducted in patients with or without NAFLD. Waist circumference (WC), body mass index (BMI), waist-to-height ratio (WHtR), Conicity Index (C Index), and lipid accumulation product (LAP) were evaluated.

Results: A total of 107 individuals were evaluated, of which 46.7% were diagnosed with NAFLD. Individuals with NAFLD presented higher values of WC, BMI, C Index, LAP, and WHtR when compared with those without NAFLD (p<0.05). For the total sample, the indicators WC, BMI, WHtR, LAP, and C Index had an area under the receiver operator characteristic curve (AUC) above 0.87, with no difference in the prediction of NAFLD in both sexes. WHtR (AUC=0.934) was the indicator of visceral adiposity with the best discriminatory power for NAFLD, followed by LAP (0.919), WC (0.912), C Index (0.907), and BMI (0.877).

Conclusions: The anthropometric clinical indicators of visceral adiposity showed high performance, especially the WHtR indicator, as NAFLD predictors.

MeSH terms

  • Adiposity
  • Body Mass Index
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Non-alcoholic Fatty Liver Disease* / diagnosis
  • Risk Factors
  • Waist Circumference
  • Waist-Height Ratio