Transcatheter Treatment of Tricuspid and Mitral Regurgitation: Similar Path, Different Stages

Cardiovasc Revasc Med. 2022 Jul:40:180-188. doi: 10.1016/j.carrev.2021.12.004. Epub 2021 Dec 9.

Abstract

Tricuspid regurgitation (TR) is frequently detected, especially in its secondary form, while primary TR is far less frequent. Similar to mitral regurgitation (MR), primary tricuspid regurgitation should require timely intervention to avoid secondary damage of the RV, which is associated with poor outcome. Current guidelines suggest that secondary TR should be treated at the time of left-sided valve surgery, although a surgical option is rarely offered to high-risk patients with combined heart valve disease. As such, while the transcatheter approach to mitral valve repair/replacement has become a major goal of the transcatheter therapies, the transcatheter tricuspid valve intervention is still at a very early stage. In this review, we provide an overview of the different stages of technical and clinical evolution of transcatheter treatment of patients with TR or MR, highlighting the challenges and the avenues for future research.

Keywords: Heart failure; Mitral valve; Transcatheter therapies; Tricuspid valve.

Publication types

  • Review

MeSH terms

  • Heart Valve Prosthesis Implantation* / adverse effects
  • Humans
  • Mitral Valve Insufficiency* / diagnostic imaging
  • Mitral Valve Insufficiency* / etiology
  • Mitral Valve Insufficiency* / surgery
  • Treatment Outcome
  • Tricuspid Valve / diagnostic imaging
  • Tricuspid Valve / surgery
  • Tricuspid Valve Insufficiency* / diagnostic imaging
  • Tricuspid Valve Insufficiency* / etiology
  • Tricuspid Valve Insufficiency* / surgery