Ultrasound-guided hyaluronic acid injection for the treatment of insertional Achilles tendinopathy: A prospective case series

Foot Ankle Surg. 2022 Oct;28(7):879-882. doi: 10.1016/j.fas.2021.12.004. Epub 2021 Dec 8.

Abstract

Background: Heel pain is a common condition and often involves the Achilles tendon and is classified as insertional or non-insertional. Several operative and non-operative treatments have been described, but there is no consensus on the most effective therapy. The aim of this study is to evaluate a case series of patients with insertional Achilles tendinopathy refractory to conservative treatment submitted to a single-dose ultrasound-guided injection of hyaluronic acid (40 mg/2.0 mL).

Methods: We prospectively included 25 patients (29 feet) who underwent a single ultrasound-guided injection of hyaluronic acid after conservative treatment failure. Clinical outcomes such as pain (using the Visual Analog Scale - VAS), function (using the American Orthopedic Foot & Ankle Society - AOFAS score), personal satisfaction, and complications were evaluated. Statistical analysis was performed using the R software.

Results: Most patients were female (80%) and there was a right-side predominance (55%). The median VAS was 8 points [range 4-10] at baseline, decreasing to 3 points [range 0-8] at the six-month follow-up, with statistical significance (p < .001). The median AOFAS score was 71 points [range 38-87] at baseline, increasing to 90 points [range 48-100] at the six-month follow-up (p < .001). The personal satisfaction level was 69%, and 48% of patients considered the result excellent. There were no Achilles tendon ruptures, infections, or allergic reactions post injection.

Conclusion: Single-dose injection of hyaluronic acid is a safe treatment option, improving function and reducing pain for six months in patients with insertional Achilles tendinopathy after conservative treatment failure.

Level of evidence: IV, case series.

Keywords: Achilles tendon; Conservative treatment; Hyaluronic acid.

MeSH terms

  • Achilles Tendon* / surgery
  • Female
  • Humans
  • Hyaluronic Acid
  • Male
  • Pain
  • Retrospective Studies
  • Tendinopathy* / diagnostic imaging
  • Tendinopathy* / drug therapy
  • Treatment Outcome
  • Ultrasonography, Interventional

Substances

  • Hyaluronic Acid