Abstract
There are no reports of systemic eosinophilic reactions to durable polymer coated drug eluting stents (DP-DES) and a consensus statement indicates that these devices should be considered in nickel allergy. We present a case of in-stent thrombosis, eosinophilia, and rash consistent with allergic myocardial infarction, a presentation of Kounis syndrome, in the context of metal allergy to DP-DES requiring long-term immunosuppression.
MeSH terms
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Aged, 80 and over
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Diagnosis, Differential
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Drug-Eluting Stents / adverse effects*
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Eosinophilia* / diagnosis
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Eosinophilia* / etiology
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Humans
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Immunosuppressive Agents / administration & dosage
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Kounis Syndrome* / diagnosis
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Kounis Syndrome* / drug therapy
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Kounis Syndrome* / etiology
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Kounis Syndrome* / physiopathology
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Male
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Metals, Heavy / adverse effects
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Metals, Heavy / analysis
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Nickel* / adverse effects
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Nickel* / analysis
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Non-ST Elevated Myocardial Infarction / surgery
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Percutaneous Coronary Intervention* / adverse effects
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Percutaneous Coronary Intervention* / instrumentation
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Percutaneous Coronary Intervention* / methods
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Prednisone / administration & dosage*
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Skin Tests / methods
Substances
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Immunosuppressive Agents
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Metals, Heavy
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Nickel
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Prednisone