Mn-Doped Quinary Ag-In-Ga-Zn-S Quantum Dots for Dual-Modal Imaging

Perizat Galiyeva; Hervé Rinnert; Sabine Bouguet-Bonnet; Sébastien Leclerc; Lavinia Balan; Halima Alem; Sébastien Blanchard; Jordane Jasniewski; Ghouti Medjahdi; Bolat Uralbekov; Raphaël Schneider

doi:10.1021/acsomega.1c05441

Mn-Doped Quinary Ag-In-Ga-Zn-S Quantum Dots for Dual-Modal Imaging

ACS Omega. 2021 Nov 23;6(48):33100-33110. doi: 10.1021/acsomega.1c05441. eCollection 2021 Dec 7.

Authors

Affiliations

¹ Université de Lorraine, CNRS, LRGP, F-54000 Nancy, France.
² Université de Lorraine, CNRS, IJL, F-54000 Nancy, France.
³ Université de Lorraine, CNRS, CRM2, F-54000 Nancy, France.
⁴ Université de Lorraine, CNRS, LEMTA, F-54000 Nancy, France.
⁵ CEMHTI-UPR 3079 CNRS, Site Haute Température, 1D Avenue de la Recherche Scientifique, 45071 Orléans, France.
⁶ Sorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, IPCM, F-75005 Paris, France.
⁷ Université de Lorraine, LIBio, F-54000 Nancy, France.
⁸ Center of Physical-Chemical Methods of Research and Analysis, Al-Farabi Kazakh National University, Al-Farabi Avenue, 71, 050040 Almaty, Kazakhstan.
⁹ LLP ≪EcoRadSM≫, Al-Farabi Avenue, 71, 050040 Almaty, Kazakhstan.
¹⁰ Laboratoire Réactions et Génie des Procédés, Université de Lorraine, 54000 Nancy, France.

Abstract

Doping of transition metals within a semiconductor quantum dot (QD) has a high impact on the optical and magnetic properties of the QD. In this study, we report the synthesis of Mn²⁺-doped Ag-In-Ga-Zn-S (Mn:AIGZS) QDs via thermolysis of a dithiocarbamate complex of Ag⁺, In³⁺, Ga³⁺, and Zn²⁺ and of Mn(stearate)₂ in oleylamine. The influence of the Mn²⁺ loading on the photoluminescence (PL) and magnetic properties of the dots are investigated. Mn:AIGZS QDs exhibit a diameter of ca. 2 nm, a high PL quantum yield (up to 41.3% for a 2.5% doping in Mn²⁺), and robust photo- and colloidal stabilities. The optical properties of Mn:AIGZS QDs are preserved upon transfer into water using the glutathione tetramethylammonium ligand. At the same time, Mn:AIGZS QDs exhibit high relaxivity (r ₁ = 0.15 mM^-1 s^-1 and r ₂ = 0.57 mM^-1 s^-1 at 298 K and 2.34 T), which shows their potential applicability for bimodal PL/magnetic resonance imaging (MRI) probes.