Recommendations of the AGG (Section Maternal Disease) for Myasthenia Gravis in Pregnancy

Geburtshilfe Frauenheilkd. 2021 Dec 8;81(12):1301-1306. doi: 10.1055/a-1541-7964. eCollection 2021 Dec.

Abstract

Myasthenia gravis is an autoimmune disease with a range of clinical presentations which manifest as combinations of weakness of the ocular, bulbar, and respiratory muscle groups and muscles of the extremities. Young women of reproductive age are most commonly affected. Preconception planning, the impact of pregnancy, prepartum management, drug therapy in pregnancy, myasthenic and cholinergic crises, fetal monitoring, peripartum management including analgesia and anesthesia during labor and cesarean section as well as neonatal management and neonatal myasthenia gravis are described here and the appropriate recommendations are given.

Keywords: labor; myasthenia gravis; neonatal features; pregnancy.