SEVERITY OF LUNG DAMAGE ASSESSED BY CT-SCAN IN RELATION TO D-DIMER LEVEL IN COVID-19

Wiad Lek. 2021;74(10 pt 1):2400-2406.

Abstract

Objective: The aim: This study was targeted to see the correlation between D-Dimer level and severity of lung injury evaluated by CT scan to prevent major complications in early of disease.

Patients and methods: Materials and methods: This study was carried out in Al-Mawani Teaching Hospital in Basra - Iraq. The study took place between August to October 2020 included 74 patients from both genders; all patients were admitted to the hospital and serial of investigations were done inform of CT scan, blood chemistry and D-dimer along with vital signs and demographic data were taken at the time of admission.

Results: Results: The correlations between the D-Dimer level and lung damage assessed by CT scan were significantly related with a P-value of less than (0.05) and regression coefficient of (3.016). Age and gender relation with severity of lung involvement were statistically non-significant. All the patients included were beyond surgical classification of ASA.

Conclusion: Conclusions: In COVID-19 infected patients, the Severity of lung injury assessed by chest computed tomography is positively correlated with D-Dimer levels, and it can be considered as an independent predictor of severe cases.

Keywords: ARDS; COVID-19; D-Dimer; GGO; anticoagulation therapy; lung damage.

MeSH terms

  • COVID-19*
  • Female
  • Fibrin Fibrinogen Degradation Products
  • Humans
  • Lung / diagnostic imaging
  • Male
  • SARS-CoV-2
  • Tomography, X-Ray Computed

Substances

  • Fibrin Fibrinogen Degradation Products
  • fibrin fragment D