A behavioural modelling approach to assess the impact of COVID-19 vaccine hesitancy

J Theor Biol. 2022 Feb 7:534:110973. doi: 10.1016/j.jtbi.2021.110973. Epub 2021 Dec 8.

Abstract

We introduce a compartmental epidemic model to describe the spread of COVID-19 within a population, assuming that a vaccine is available, but vaccination is not mandatory. The model takes into account vaccine hesitancy and the refusal of vaccination by individuals, which take their decision on vaccination based on both the present and past information about the spread of the disease. Theoretical analysis and simulations show that voluntary vaccination can certainly reduce the impact of the disease but is unable to eliminate it. We also demonstrate how the information-related parameters affect the dynamics of the disease. In particular, vaccine hesitancy and refusal are better contained in case of widespread information coverage and short-term memory. Finally, the possible impact of seasonality on the spread of the disease is investigated.

Keywords: Human behaviour; Infectious disease; Seasonality; Stability; Vaccination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19 Vaccines
  • COVID-19*
  • Humans
  • SARS-CoV-2
  • Vaccination
  • Vaccination Hesitancy
  • Vaccines*

Substances

  • COVID-19 Vaccines
  • Vaccines