Proving that a genome-edited organism is not GMO

Megumi Ishii; Tetsuya Ishii

doi:10.1016/j.tibtech.2021.11.001

Proving that a genome-edited organism is not GMO

Trends Biotechnol. 2022 May;40(5):525-528. doi: 10.1016/j.tibtech.2021.11.001. Epub 2021 Dec 7.

Authors

Megumi Ishii¹, Tetsuya Ishii²

Affiliations

¹ Office of Health and Safety, Hokkaido University, Sapporo 060-0808, Japan.
² Office of Health and Safety, Hokkaido University, Sapporo 060-0808, Japan. Electronic address: tishii@general.hokudai.ac.jp.

PMID: 34893376
DOI: 10.1016/j.tibtech.2021.11.001

Abstract

A genome-edited agricultural product that is proven to contain no exogenous DNA is not subject to genetically modified organism (GMO) regulations in some countries. However, whether such proof is definitive is often disputed. We discuss the approaches to substantially proving that a genome-edited organism is not GMO, while considering social aspects.

Keywords: GMO; agriculture; genome-editing; negative proof; regulation; society.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Agriculture
Crops, Agricultural* / genetics
Food, Genetically Modified*
Gene Editing
Genome
Plants, Genetically Modified / genetics