An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation

Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov:2021:4213-4217. doi: 10.1109/EMBC46164.2021.9629950.

Abstract

The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorbable Implants
  • Angioplasty, Balloon, Coronary*
  • Clinical Trials as Topic
  • Drug-Eluting Stents*
  • Humans
  • Time Factors