Chemical Composition and Antifungal Activity of Myrcia multiflora and Eugenia florida Essential Oils

Molecules. 2021 Nov 30;26(23):7259. doi: 10.3390/molecules26237259.

Abstract

The essential oils of three specimens of Myrcia multiflora (A, B and C) and Eugenia florida were extracted by hydrodistillation, and the chemical compositions from the essential oils were identified by gas chromatography and flame ionization detection (CG/MS and CG-FID). The fungicide potential of the EOs against five fungicide yeasts was assessed: Candida albicans INCQS-40175, C. tropicalis ATCC 6258, C. famata ATCC 62894, C. krusei ATCC 13803 and C. auris IEC-01. The essential oil of the specimen Myrcia multiflora (A) was characterized by the major compounds: α-bulnesene (26.79%), pogostol (21.27%) and δ-amorphene (6.76%). The essential oil of the specimen M. multiflora (B) was rich in (E)-nerolidol (44.4%), (E)-γ-bisabolene (10.64%) and (E,E)-α-farnesene (8.19%), while (E)-nerolidol (92.21%) was the majority of the specimen M. multiflora (C). The sesquiterpenes seline-3,11-dien-6-α-ol (12.93%), eremoligenol (11%) and γ-elemene (10.70%) characterized the chemical profile of the EOs of E. florida. The fungal species were sensitive to the essential oil of M. multiflora (B) (9-11 mm), and the lowest inhibitory concentration (0.07%) was observed in the essential oil of M. multiflora (A) against the yeasts of C. famata. Fungicidal action was observed in the essential oils of M. multiflora (A) against C. famata, with an MIC of 0.78 µL/mL and 3.12 µL/mL; C. albicans, with an MFC of 50 µL/mL and M. multiflora (C) against C. albicans; and C. krusei, with a MFC of 50 µL/mL.

Keywords: antifungal action; essential oil; inhibition potential; pathogens; volatile compounds.

MeSH terms

  • Anti-Infective Agents / pharmacology
  • Antifungal Agents / chemistry*
  • Antifungal Agents / pharmacology*
  • Eugenia / chemistry*
  • Microbial Sensitivity Tests
  • Myrtaceae / chemistry*
  • Oils, Volatile / chemistry*
  • Oils, Volatile / pharmacology*
  • Plant Extracts / pharmacology
  • Principal Component Analysis
  • Yeasts / drug effects

Substances

  • Anti-Infective Agents
  • Antifungal Agents
  • Oils, Volatile
  • Plant Extracts