Fusarium Keratitis-Review of Current Treatment Possibilities

J Clin Med. 2021 Nov 23;10(23):5468. doi: 10.3390/jcm10235468.

Abstract

In many parts of the world, fungi are the predominant cause of infectious keratitis; among which, Fusarium is the most commonly isolated pathogen. The clinical management of this ophthalmic emergency is challenging. Due to the retardation of the first symptoms from an injury and the inability to differentiate fungal from bacterial infections based on clinical symptoms and difficult microbial diagnostics, proper treatment, in many cases, is postponed. Moreover, therapeutical options of Fusarium keratitis remain limited. This paper summarizes the available treatment modalities of Fusarium keratitis, including antifungals and their routes of administration, antiseptics, and surgical interventions.

Keywords: Fusarium keratitis; Fusarium keratitis treatment; amphotericin B; natamycin; voriconazole.

Publication types

  • Review