Comparison of chromatographic performance of co-grafted silica using octadecene respectively with vinylpyrrolidone, vinylimidazole and vinylpyridine

Chao Fan; Kaijun Quan; Jia Chen; Hongdeng Qiu

doi:10.1016/j.chroma.2021.462690

Comparison of chromatographic performance of co-grafted silica using octadecene respectively with vinylpyrrolidone, vinylimidazole and vinylpyridine

J Chromatogr A. 2022 Jan 4:1661:462690. doi: 10.1016/j.chroma.2021.462690. Epub 2021 Nov 18.

Authors

Chao Fan¹, Kaijun Quan², Jia Chen², Hongdeng Qiu³

Affiliations

¹ CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China; University of Chinese Academy of Sciences, Beijing 100049, China.
² CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
³ CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China; University of Chinese Academy of Sciences, Beijing 100049, China; College of Chemistry, Zhengzhou University, Zhengzhou 450001, China. Electronic address: hdqiu@licp.cas.cn.

PMID: 34883356
DOI: 10.1016/j.chroma.2021.462690

Abstract

Three reversed-phase liquid chromatography (RPLC) stationary phases were obtained by using long-chain 1-octadecene (OD) co-grafted with three short-chain monomers, including N-vinylpyrrolidone (NVP), 1-vinylimidazole (VIm) and 4-vinylpyridine (VPy), respectively (noted as Sil@ODNVP, Sil@ODVIm and Sil@ODVPy). Peak broadening phenomenon in RPLC mode which resulted by short-chain was examined carefully. Compared with Sil@ODNVP, both of Sil@ODVIm and Sil@ODVPy had smaller peak width and higher column efficiency in the separation of 10 polycyclic aromatic hydrocarbons (PAHs), 7 alkyl benzenes, 7 aromatic acids, 7 aromatic esters and 9 phenols. In addition, VPy has the strongest ion exchange capacity than other two short-chains. In this case, we can see that VPy and VIm maybe more suitable to be used as functional monomeric modifiers of new chromatographic stationary phases.

Keywords: 1-Vinylimidazole; 1-octadecene; 4-Vinylpyridine; N-vinylpyrrolidone; Stationary phase.

MeSH terms

Alkenes
Chromatography, High Pressure Liquid
Chromatography, Reverse-Phase
Polycyclic Aromatic Hydrocarbons*
Polymers
Silicon Dioxide*

Substances

Alkenes
Polycyclic Aromatic Hydrocarbons
Polymers
Silicon Dioxide