Granulomatous-lymphocytic interstitial lung disease: an international research prioritisation

John R Hurst; S Hamza Abbas; Heba M Bintalib; Tiago M Alfaro; Ulrich Baumann; Siobhan O Burns; Alison Condliffe; Jesper R Davidsen; Børre Fevang; Andrew R Gennery; Filomeen Haerynck; Joseph Jacob; Stephen Jolles; Olivia Lamers; Anne Bergeron; Marion Malphettes; Véronique Meignin; Cinzia Milito; Tomas Milota; Martine Pergent; Antje Prasse; Isabella Quinti; Elisabetta Renzoni; Anna Sediva; Daiana Stolz; Bas Smits; Friedolin Strauss; Annick A J M van de Ven; Joris van Montfrans; Klaus Warnatz

doi:10.1183/23120541.00467-2021

Granulomatous-lymphocytic interstitial lung disease: an international research prioritisation

ERJ Open Res. 2021 Dec 6;7(4):00467-2021. doi: 10.1183/23120541.00467-2021. eCollection 2021 Oct.

Authors

John R Hurst¹, S Hamza Abbas¹, Heba M Bintalib¹, Tiago M Alfaro², Ulrich Baumann³, Siobhan O Burns^{4

5}, Alison Condliffe⁶, Jesper R Davidsen⁷, Børre Fevang^{8

9}, Andrew R Gennery^{10

11}, Filomeen Haerynck¹², Joseph Jacob^{1

13}, Stephen Jolles¹⁴, Olivia Lamers¹⁵, Anne Bergeron¹⁶, Marion Malphettes¹⁷, Véronique Meignin¹⁸, Cinzia Milito¹⁹, Tomas Milota^{20

21}, Martine Pergent²², Antje Prasse^{23

24

25}, Isabella Quinti¹⁹, Elisabetta Renzoni²⁶, Anna Sediva^{20

21}, Daiana Stolz²⁷, Bas Smits²⁸, Friedolin Strauss²⁹, Annick A J M van de Ven^{30

31}, Joris van Montfrans^{30

31}, Klaus Warnatz^{32

33}

Affiliations

¹ UCL Respiratory, University College London, London, UK.
² Unit of Pneumology, Coimbra Hospital and Universitary Centre, Coimbra, Portugal.
³ Paediatric Pulmonology, Allergy and Neonatology, Hanover Medical School, Hannover, Germany.
⁴ Institute of Immunity and Transplantation, University College London, London, UK.
⁵ Dept of Immunology, Royal Free London NHS Foundation Trust, London, UK.
⁶ Dept of Infection, Immunity and Cardiovascular Diseases, University of Sheffield, Sheffield, UK.
⁷ South Danish Centre for Interstitial Lung Diseases (SCILS), Dept of Respiratory Medicine, Odense University Hospital, Odense, Denmark.
⁸ Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Oslo, Norway.
⁹ Research Institute of Internal Medicine, Oslo University Hospital, Oslo, Norway.
¹⁰ Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
¹¹ Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne, UK.
¹² Dept of Pediatric Pulmonology and Immunology, Jeffrey Modell Foundation Diagnostic and Research Centre, PID Research lab, Ghent University Hospital, Ghent University, Ghent, Belgium.
¹³ Centre for Medical Image Computing, University College London, London, UK.
¹⁴ Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, UK.
¹⁵ Dept of Parasitology, Leiden University Medical Center, Leiden, The Netherlands.
¹⁶ Université de Paris, Hôpital Saint-Louis, AP-HP, Pulmonology Dept, Paris, France.
¹⁷ Immunology Dept, Inserm U1126, Hôpital Saint-Louis, APHP, Paris, France.
¹⁸ Dept of Pathology, Hôpital Saint-Louis, APHP, Paris, France.
¹⁹ Dept of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
²⁰ Second Faculty of Medicine, Charles University, Prague, Czech Republic.
²¹ Motol University Hospital, Prague, Czech Republic.
²² International Patient Organisation for Primary Immunodeficiencies, Brussels, Belgium.
²³ Dept of Pulmonology, Hannover Medical School, Hannover, Germany.
²⁴ DZL BREATH, Hannover, Germany.
²⁵ Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.
²⁶ Interstitial Lung Disease Unit, Royal Brompton Hospital/Imperial College London, London, UK.
²⁷ University Hospital Basel, Clinic of Respiratory Medicine and Pulmonary Cell Research, Basel, Switzerland.
²⁸ Dept of Pediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht, The Netherlands.
²⁹ dsai e.V. Patientenorganisation fuer angeborene Immundefekte, Schnaitsee, Germany.
³⁰ Dept of Internal Medicine and Allergology, University Medical Centre Groningen, Groningen, The Netherlands.
³¹ Dept of Rheumatology and Clinical Immunology, University Medical Centre Groningen, Groningen, The Netherlands.
³² Dept of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
³³ Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Abstract

The first ever research prioritisation exercise in GLILD: this survey identified areas of interest in the diagnosis, treatment and management of GLILD, which can be used as a roadmap for future research https://bit.ly/3nVuzti.

Grants and funding

209553/Z/17/Z/WT_/Wellcome Trust/United Kingdom