Effects of Psychological Intervention on Perioperative Quality of Life and Serum PSA and FPSA Levels of Patients with Prostate Cancer Treated with Integrated Traditional Chinese and Western Medicine

Xifeng Sun; Yi Lu; Hongxia Zhu; Rui Li; Donghua Zhang; Kunfang Pang

doi:10.1155/2021/9286905

Effects of Psychological Intervention on Perioperative Quality of Life and Serum PSA and FPSA Levels of Patients with Prostate Cancer Treated with Integrated Traditional Chinese and Western Medicine

Evid Based Complement Alternat Med. 2021 Nov 26:2021:9286905. doi: 10.1155/2021/9286905. eCollection 2021.

Authors

Xifeng Sun¹, Yi Lu², Hongxia Zhu³, Rui Li⁴, Donghua Zhang⁵, Kunfang Pang⁶

Affiliations

¹ Department of Clinical Laboratory, Weifang People's Hospital, Weifang 261041, China.
² Sterilization Supply Room, Qingdao Eighth People's Hospital, Qingdao 266000, China.
³ Department of Operation Room, Rizhao Hospital of TCM, Rizhao 276800, China.
⁴ Department of Endocrinology, Zhangqiu District People's Hospital, Jinan 250200, China.
⁵ Tumor-chemotherapy Department, Zhangqiu District People's Hospital, Jinan 250200, China.
⁶ Department of Anesthesiology, Qingdao Hospital of Traditional Chinese Medicine, Qingdao Hiser Hospital, Qingdao 266033, China.

Abstract

Objective: To observe the effects of psychological intervention on the perioperative quality of life and serum prostate-specific antigen (PSA) and free PSA (FPSA) levels in patients with prostate cancer treated with integrated traditional Chinese and Western medicine.

Method: A total of 208 prostate cancer patients were selected and randomly divided into a study group with 104 cases and a control group with 104 cases. The control group received a plan of basic nursing combined with integrated traditional Chinese and Western medicine, and the study group received psychological intervention on the basis of the control group. Negative emotion, pain degree, quality of life, maximum urine flow rate, residual urine volume, International Prostate Symptom Score (IPSS), and incidence of adverse reactions were compared between the two groups before and after the treatment. The levels of PSA and FPSA and the long-term efficacy of the two groups of patients before and after treatment were compared.

Results: After nursing, Hamilton Anxiety Scale (HAMA) score, Hamilton Depression Scale (HAMD) score, pain degree, maximum urine flow rate, residual urine volume, IPSS score, emotional function, social function, role function, and physical function scores of patients in two groups were decreased, and the decrease was more significant in the study group. After treatment, serum PSA and FPSA levels in the study group were obviously lower than those in the control group. The two-year cumulative survival rate of the study group was higher than that of the control group. There was no significant difference in the cognitive function score and incidence of adverse reactions between the two groups.

Conclusion: Psychological intervention combined with traditional Chinese and Western medicine in the treatment of prostate cancer can effectively improve the patient's psychological state, reduce the degree of pain in patients, improve the therapeutic effect and the quality of life of patients, and significantly reduce serum PSA and FPSA levels, which could lead to a prolonged life.