[FibroTouch diagnostic efficiency and influencing factors for liver fibrosis in autoimmune liver diseases]

Zhonghua Gan Zang Bing Za Zhi. 2020 Dec 20;28(12):1048-1051. doi: 10.3760/cma.j.cn501113-20190822-00313.
[Article in Chinese]

Abstract

FibroTouch (FT) has been used widely in clinic. Studies of the FT diagnostic efficiency and influencing factors of liver stiffness measurement (LSM) of liver fibrosis in autoimmune liver diseases (AILD) have shown that FT has a good diagnostic efficiency and accuracy, especially in AIH. However, for patients with primary biliary cholangitis and overlap syndrome of autoimmune hepatitis, FT results should be vigilant. In addition, the diagnostic efficiency of FT. Notably, when using FT to diagnose AILD, the value of elastic stiffness depends on five influencing factors, such as, age, total bile acid, international standardized ratio, FIB-4 index, and prothrombin time.

FibroTouch(FT)已被广泛投入临床使用,在研究FT对自身免疫性肝病(AILD)肝纤维化的诊断效能及分析影响肝脏硬度值(LSM)的因素中发现,FT对AILD肝纤维化具有良好的诊效效能,尤其对AIH肝纤维化具有良好的诊断准确性,但用于原发性胆汁性胆管炎及其与自身免疫性肝炎重叠综合征患者时,需谨慎对待结果。与血清学模型比较,FT的诊断效能与Forns指数相当。FT用于诊断AILD时,其弹性硬度值受年龄、总胆汁酸、凝血酶原时间标准化比值、纤维蛋白原指数、凝血酶原时间5个因素影响。.

Keywords: Autoimmune liver disease; Liver biopsy; Liver fibrosis; Transient elastography.

MeSH terms

  • Hepatitis, Autoimmune* / complications
  • Hepatitis, Autoimmune* / diagnosis
  • Humans
  • Liver Cirrhosis / diagnosis
  • Liver Cirrhosis, Biliary* / complications
  • Liver Cirrhosis, Biliary* / diagnosis
  • Liver Diseases*
  • ROC Curve