Comparative analysis of measurements of the anterior segment and the axial length parameters of the eyeball obtained with optical and ultrasound technique

Expert Rev Med Devices. 2021 Dec;18(12):1245-1253. doi: 10.1080/17434440.2021.2012448. Epub 2021 Dec 3.

Abstract

Purpose: To compare anterior chamber depth (ACD), keratometry (K1, K2), central corneal thickness (CCT), and axial length (AL) measured by four different devices.

Material and methods: 150 eyes qualified for cataract surgery were included in the study. Four devices: IOL Master 500, OCT CASIA2, Dual Scheimpflug Analyzer Galilei G6, and Quantel Compact Touch ultrasound biometer, were compared. The agreement of measurements between the devices was evaluated by the Bland-Altman method.

Results: ACD was significantly different for Ultrasound and IOL Master 3 ± 0.33 3.12 ± 0.42 respectively Interclass correlation ecoefficiency (ICC):0.69 (95% confidence interval (CI): 0.62; 0.76) p < 0.001. A significant difference was observed between Casia and IOL while measuring K1, 43.5 ± 1.7 vs. 43.61 ± 1.56 ICC:0.84 (95%CI: 0.79; 0.87) and ACD parameters 2.65 ± 0.45 vs. 3.12 ± 0.42 ICC 0.68 (95%: 0.6; 0.75) and K2 42.51 ± 1.62 vs. 44.57 ± 1.59 ICC; 0.83 (95%CI:0.78; 0.87) p < 0.001. Similarly, measurements obtained by Casia, and Galilei were also different K1 43.5 ± 1.7 ICC:0.7 (95%CI:0.62; 0.76), CCT 546.35 ± 34.75 vs. 566.73 ± 37.92 ICC:0.88 (95%CI:0.84; 0.9) p < 0.001. Differences between Galilei and IOL master were not significant p values from 0.175 to 0.999 ICC 0.8 (95%CI:0.75; 0.85) to ICC 0.94 (95%CI:0.92; 0.95).

Conclusions: The measurements obtained from Casia, and Ultrasound were significantly different and not interchangeable except for IOL master and Galilei.

Keywords: IOL master 500; Keratometry; anterior chamber depth; axial length; cataract surgery; central corneal thickness; dual scheimpflug analyzer galilei G6; quantel compact touch a-scan ultrasound biometer; ss-OCT casia 2.

MeSH terms

  • Biometry*
  • Cornea / diagnostic imaging
  • Humans
  • Reproducibility of Results
  • Tomography, Optical Coherence*
  • Ultrasonography