Cryoablation in Locoregional Management of Complex Unresectable Chest Neoplasms

Tomography. 2021 Nov 1;7(4):688-696. doi: 10.3390/tomography7040057.

Abstract

Rationale and objectives: The aim of our retrospective study was to assess the safety and feasibility of cryoablation in high-risk patients with complex chest neoplastic lesions.

Materials and methods: Twenty patients with complex chest malignancies, both primary and secondary, located in the mediastinum, lung, and chest wall, underwent percutaneous CT-guided cryoablation treatments. Procedural success as well as complications were evaluated.

Results: A total of 24 neoplastic lesions were treated (mean diameter: 27 mm; range: 7-54 mm). Technical success was obtained in all patients, without major complications or intraprocedural death. A pneumothorax not requiring a drainage tube placement was registered in 50% of patients, while 3/24 patients had a grade 3 pneumothorax requiring a chest tube placement.

Conclusion: Percutaneous CT-guided cryoablation seems a safe and feasible treatment for complex thoracic lesions.

Keywords: cryoablation; interventional radiology; lung tumors.

MeSH terms

  • Cryosurgery* / adverse effects
  • Humans
  • Pneumothorax* / diagnostic imaging
  • Pneumothorax* / etiology
  • Retrospective Studies
  • Thoracic Neoplasms* / diagnostic imaging
  • Thoracic Neoplasms* / surgery
  • Tomography, X-Ray Computed