[Microbe-gut-brain axis and neurological disorders: a review]

Sheng Wu Gong Cheng Xue Bao. 2021 Nov 25;37(11):3781-3788. doi: 10.13345/j.cjb.200773.
[Article in Chinese]

Abstract

Intestinal microbes have an adjuvant therapeutic effect on neurological disorders (such as Parkinson's, depression, and Alzheimer's disease). It affects brain function and host behavior through the neural pathways, the immune pathways and the microbial metabolites, the so-called gut-brain axis. This article summarizes the recent advances in the role of the microbe-gut-brain axis in neurological disorders, in order to provide new ideas for the treatment of neurodegenerative diseases.

Keywords: fecal bacteria transplantation; gut-brain axis; intestinal microbes; neurological disorders; probiotic/prebiotic therapy.

Publication types

  • Review

MeSH terms

  • Brain
  • Environment
  • Gastrointestinal Microbiome*
  • Humans
  • Neurodegenerative Diseases*