Leser-Trelat sign preceding male breast cancer

Soraya Aouali; Sara Bensalem; Hasnae Saddouk; Asmae Aissaoui; Amal Bennani; Nada Zizi; Siham Dikhaye

doi:10.1016/j.amsu.2021.103065

Leser-Trelat sign preceding male breast cancer

Ann Med Surg (Lond). 2021 Nov 13:72:103065. doi: 10.1016/j.amsu.2021.103065. eCollection 2021 Dec.

Authors

Soraya Aouali¹, Sara Bensalem¹, Hasnae Saddouk¹, Asmae Aissaoui², Amal Bennani², Nada Zizi^{1

3}, Siham Dikhaye^{1

3}

Affiliations

¹ Department of Dermatology, Mohammed the VI University Hospital of Oujda, Morocco.
² Pathology Laboratory, Mohammed the VIth, University Hospital of Oujda, Morocco.
³ Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy, Mohamed the First University of Oujda, Oujda, Morocco.

Abstract

Introduction: Leser-Trelat sign is a paraneoplastic marker characerized by the abrupt appearance of seborrheic keratoses. It is described in association with many underlying malignant diseases.

Case report: We report a case of coexistence of two rare entities, represented by the Leser-Trelat sign occurring with male breast cancer.

Discussion: The asscociation of male breast cancer and LT sign is decidedly unusual. To our knowledge, our case report is the second to describe the association of these two rare entities.

Conclusion: A proper dermatological examination and a good knowledge of cutaneous paraneoplastic syndromes can be of great help in screening for multiple skin cancers.

Keywords: Leser-Trélat sign; Male breast cancer; Paraneoplastic dermatoses.

Publication types

Case Reports