The clinical efficacy of low-dose whole-lung irradiation in moderate-to-severe COVID-19 pneumonia: RTMX-20 trial

Cindy S Ortiz; Diana Hernández; Cesar Trujillo; David Calderón; Placido Esqueda; Flavio Calva; Arcadio Betancourt; Miriam Ramírez; Graciela Cervantes; Miguel A Souto; Juan G Celis; Luis R Nolazco; Alejandro Olmos

doi:10.1016/j.radonc.2021.11.013

The clinical efficacy of low-dose whole-lung irradiation in moderate-to-severe COVID-19 pneumonia: RTMX-20 trial

Radiother Oncol. 2022 Jan:166:133-136. doi: 10.1016/j.radonc.2021.11.013. Epub 2021 Nov 25.

Affiliations

¹ Radiation Oncology Department, UMAE 1, Speciality Hospital, Bajio National Medical Center, Instituto Mexicano del Seguro Social, Mexico.
² Internal Medicine Department, UMAE 1, Speciality Hospital, Bajio NationalMedical Center, Instituto Mexicano del Seguro Social, Mexico.
³ Medical Physics Department, UMAE 1, Speciality Hospital, Bajio National Medical Center, Instituto Mexicano del Seguro Social, Mexico.
⁴ Radiation Oncology Department, UMAE 25, Speciality Hospital, Instituto Mexicano del Seguro Social, Mexico.
⁵ Direction, UMAE 1, Speciality Hospital, Bajio National Medical Center, Instituto Mexicano del Seguro Social, Mexico.
⁶ Radiation Oncology Department, UMAE 1, Speciality Hospital, Bajio National Medical Center, Instituto Mexicano del Seguro Social, Mexico. Electronic address: alex_olmos13@hotmail.com.

Abstract

This is a paired prospective comparative cohort study with 58 patients, in order to analyze the clinical LD-WLI in patients with moderate or severe COVID19 pneumonia. The results of this study show that the Radiotherapy could be an option to improve the clinical response for patients with COVID-19.

Keywords: Acute respiratory distress syndrome (ARDS); COVID-19; Low dose radiotherapy (LDRT); SARS-CoV2.

Publication types

Clinical Trial

MeSH terms

COVID-19* / radiotherapy
Cohort Studies
Humans
Lung / radiation effects
Prospective Studies
SARS-CoV-2
Treatment Outcome