Localized Well-Differentiated Rectal Neuroendocrine Tumors - Where Are We in 2021?

Larissa Costa Amorim; Artur Rodrigues Ferreira; Rodrigo Oliva Perez; Renata D'Alpino Peixoto

doi:10.1016/j.clcc.2021.10.002

Localized Well-Differentiated Rectal Neuroendocrine Tumors - Where Are We in 2021?

Clin Colorectal Cancer. 2022 Mar;21(1):e22-e27. doi: 10.1016/j.clcc.2021.10.002. Epub 2021 Oct 16.

Authors

Larissa Costa Amorim¹, Artur Rodrigues Ferreira², Rodrigo Oliva Perez³, Renata D'Alpino Peixoto²

Affiliations

¹ Centro Paulista de Oncologia (Grupo Oncoclínicas), São Paulo, Brazil. Electronic address: lah.costaamorim@gmail.com.
² Centro Paulista de Oncologia (Grupo Oncoclínicas), São Paulo, Brazil.
³ Hospital alemão Oswaldo Cruz, Colorectal Surgery Division, São Paulo, Brazil; Hospital Beneficência Portuguesa, Surgical Oncology Division, São Paulo, Brazil; Angelita & Joaquim Gama Institute, São Paulo, Brazil.

PMID: 34838461
DOI: 10.1016/j.clcc.2021.10.002

Abstract

Neuroendocrine tumors (NETs) are slow-growing malignancies with distinct biologic and clinical characteristics. Most rectal-NETs are localized and well-differentiated, usually carrying an excellent prognosis. In this review, we aim at describing the epidemiology, clinical characteristics and therapeutic approaches for well-differentiated rectal NETs.

Keywords: Gastrointestinal tumors; NETs; Neuroendocrine neoplasms; Rectal NETs; Rectal carcinoids.

Publication types

Review

MeSH terms

Humans
Neuroendocrine Tumors* / diagnosis
Neuroendocrine Tumors* / epidemiology
Neuroendocrine Tumors* / therapy
Prognosis
Rectal Neoplasms* / diagnosis
Rectal Neoplasms* / epidemiology
Rectal Neoplasms* / therapy
Rectum / pathology